Robert F. Furchgott

From PhysicsWiki
Jump to: navigation, search
Robert F. Furchgott
Drfurchgott.jpg
Born Robert Francis Furchgott
June 4, 1916
Charleston, South Carolina
Died May 19, 2009(2009-05-19) (aged 92)
Seattle, Washington
Nationality United States
Citizenship American
Spouse(s) Lenore Mandelbaum (1941-1983; her death; 3 children)
Margaret Gallagher Roth (?-2006; her death)
Awards Nobel Prize in Physiology or Medicine in 1998
Scientific career
Fields biochemistry
Institutions

SUNY Downstate Medical Center 1956-2009

Washington University in St. Louis 1949-1956
Signature
Robert F. Furchgott.jpg

Robert Francis Furchgott (June 4, 1916 – May 19, 2009) was a Nobel Prize-winning American biochemist.

Life and career

Furchgott was born in Charleston, South Carolina, to Arthur Furchgott (December 1884 - January 1971), a department store owner, and Pena (Sorentrue) Furchgott. He graduated with a degree in chemistry in 1937 from the University of North Carolina at Chapel Hill, received his Ph.D in biochemistry at Northwestern University in 1940. He was faculty member of Washington University School of Medicine from 1949 to 1956. From 1956 to 2009, he was professor of pharmacology at the State University of New York Downstate Medical Center.

In 1978, Furchgott discovered a substance in endothelial cells that relaxes blood vessels, calling it endothelium-derived relaxing factor (EDRF). By 1986, he had worked out EDRF's nature and mechanism of action, and determined that EDRF was in fact nitric oxide (NO), an important compound in many aspects of cardiovascular physiology. This research was important in explaining the action of Viagra, treatment of blue babies, and other medical and health-related issues.

In addition to the Nobel Prize in Physiology or Medicine he shared in 1998 (with Louis Ignarro and Ferid Murad), Furchgott also received a Gairdner Foundation International Award for his groundbreaking discoveries (1991) and the Albert Lasker Award for Basic Medical Research (1996), the latter also with Ferid Murad.

Furchgott, who was Jewish,[1] lived for most of his married and career life in Woodmere, NY (Long Island). He was married to Lenore Mandelbaum (February 1915 - April 1983)[2] from 1941 until she died aged 68. They had three daughters: Jane, Susan and Terry. His daughter, Susan, was a prolific artist in the San Francisco counter culture and a co-founder of the Kerista Commune (she was also known as "Even Eve" and "Eve Furchgott"). Robert Furchgott later married Margaret Gallagher Roth, who died March 14, 2006.[3] He served as a professor emeritus at the State University of New York Downstate Medical Center. In 2008 he moved to Seattle's Ravenna neighborhood. Furchgott died on May 19, 2009[4] in Seattle. He is survived by his three daughters, four grandchildren, and one great-grandchild.

See also

References

  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.
  • Lua error in Module:Citation/CS1 at line 746: Argument map not defined for this variable.

External links